| Date | Opponent | Time/TV | Tickets | |
| Saturday Sep. 2, 2017 |  | Temple Owls Notre Dame Stadium, South Bend, IN | 3:30 PM ET NBC | Won 49-16 |
| Saturday Sep. 9, 2017 |  | Georgia Bulldogs Notre Dame Stadium, South Bend, IN | 7:30 PM ET NBC | Lost 20-19 |
| Saturday Sep. 16, 2017 |  | Boston College Eagles Alumni Stadium, Chestnut Hill, MA | Time: TBA TV: TBA | Won 49-20 |
| Saturday Sep. 23, 2017 |  | Michigan State Spartans Spartan Stadium, East Lansing, MI | 8:00 PM ET | Won 38-18 |
| Saturday Sep. 30, 2017 |  | Miami (OH) RedHawks Notre Dame Stadium, South Bend, IN | 5:00 PM ET NBCSN | Won 52-17 |
| Saturday Oct. 7, 2017 |  | North Carolina Tar Heels Kenan Memorial Stadium, Chapel Hill, NC | 3:30 PM ET | Won 33-10 |
| Saturday Oct. 14, 2017 | Bye Week | |||
| Saturday Oct. 21, 2017 |  | USC Trojans Notre Dame Stadium, South Bend, IN | 7:30 PM ET NBC | Won 49-14 |
| Saturday Oct. 28, 2017 |  | NC State Wolfpack Notre Dame Stadium, South Bend, IN | 3:30 PM ET NBC | Won 35-14 |
| Saturday Nov. 4, 2017 |  | Wake Forest Demon Deacons Notre Dame Stadium, South Bend, IN | 3:30 PM ET NBC | Won 48-37 |
| Saturday Nov. 11, 2017 |  | Miami (FL) Hurricanes Sun Life Stadium, Miami Gardens, FL | Time: TBA TV: TBA | Lost 41-8 |
| Saturday Nov. 18, 2017 |  | Navy Midshipmen Notre Dame Stadium, South Bend, IN | 3:30 PM ET NBC | Won 24-17 |
| Saturday Nov. 25, 2017 |  | Stanford Cardinal Stanford Stadium, Stanford, CA | Time: TBA TV: TBA | Lost 38-20 |
| Monday Jan. 1, 2018 |  | Citrus Bowl LSU Tigers Camping World Stadium, Orlando, FL | 1:00 PM ET | Won 21-17 |
